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HUBEI PHARMAGRADE STEROIDS., LTD
HUBEI PHARMAGRADE STEROIDS., LTD
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99% Purity Pharmaceutical Raw Materials Raw Powder Pirfenidone PFD CAS 53179-13-8

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HUBEI PHARMAGRADE STEROIDS., LTD
City: Wuhan
Province/State: Hubei
Country/Region: China
Tel: 00-86-13632880526
Contact Person:
Miss Emily

99% Purity Pharmaceutical Raw Materials Raw Powder Pirfenidone PFD CAS 53179-13-8

Brand Name : YC
Model Number : CAS: 53179-13-8
Certification : USP, ISO9001, FDA, etc.
Place of Origin : WUHAN CHINA
MOQ : 10g
Price : Negotiation
Payment Terms : T/T, Western Union, MoneyGram, BitCoin
Supply Ability : 1000kg per month
Delivery Time : 4--7 working days
Packaging Details : According to your requirements (foil bag, drums, disguised packages, etc.)
CAS : 53179-13-8
Purity : 99%
Appearance : white powder
Payment : T/T, MoneyGram, Western Union, BitCoin
Package : According to your requirements
Usage : for Nootropics
Service : 7/24
Contact Now

Pharmaceutical Raw Materials Raw Powder Pirfenidone PFD CAS 53179-13-8


Product Description:
Pirfenidone
CAS: 53179-13-8
MF: C12H11NO
FW:185.22
Other Name: 5-Methyl-N-phenyl-2-1H-pyridone
Appearance: White crystal powder
Melting point: 102--109
Solubility: DMSO: 10 mg/mL, soluble
Loss on drying <1.0%
Known single impurity <1.0%
Unknown single impurity <0.5%
Total impurity <2.0%
Assay(as dried) 99%min


Application:
In vitro, pirfenidone can inhibit the uterine flesh tumour cells and leiomyoma cells proliferation. Pirfenidone can inhibit the TGF - beta - 1 inducing fibroblast collagen formation. Inhibition of PDGF, FGF and TGF - beta - 1 inducing fibroblast proliferation. In hamster model, pirfenidone, taken by mouth, that can the prevention and treatment of pulmonary fibrosis induced by bleomycin. Pirfenidone can prevent the sclerosing peritonitis in rats induced by chemical, can also be keloid grafting for the treatment of nude mice. Pirfenidone 0.01 1 mg/ml can suppress the matrix and dose dependent manner serum stimulate uterine fibroids and leiomyoma cell DNA synthesis, the compound has no cytotoxic effect, has no effect on collagen mRNA level also. Pirfenidone in hamster pulmonary fibrosis model can reduce the disease before the collagen I mRNA level enhancement, reduce the level of the lung hydroxyproline and malondialadehyde and lung preserved ammonia acyl hydroxylase activity.


Whatsapp: +8613632880526

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Email: Emily@chembj.com


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